NicoDerm® CQ® Patch
Doubles your patients’ chances of quitting.1* Provides sustained nicotine delivery over 24 hours 2,3 to your patients throughout their day.
Pharmacokinetics of NicoDerm® CQ®
Not all nicotine patches are the same2,3
It is important to recommend the NicoDerm® CQ® Patch by name. The NicoDerm® CQ® Patch is the only patch with time-release SmartControl® Technology.4
1 OCCLUSIVE BACKING (clear)
Covers nicotine and helps prevent nicotine evaporation
2 DRUG RESERVOIR
Stores therapeutic nicotine, which helps prevent the urge to smoke all day long
3 RATE-CONTROLLING MEMBRANE
Provides a steady stream of therapeutic nicotine to help prevent nicotine cravings
4 ADHESIVE AND RELEASE LINER
Contains a loading bolus to provide patients with nicotine right from the start
Dosing Information for
and How to Use
the NicoDerm® CQ® Patch
Advise patients to read and follow label directions. Behavioral support may increase their chances of success.
*As compared with placebo.
†Study design: A crossover study with 25 subjects assigned to receive treatment in random sequence to 4 test products: 4-mg gum, 15-mg patch, or one of two 21-mg patches. Subjects with patches were further randomized to wear the patch for either 16 or 24 hours daily for the 3-day treatment phase. Parameters were total nicotine absorbed (AUC0-24: area under the concentration curve [Cmax]), minimum plasma nicotine concentration (Cmin), and the time to reach Cmax (Tmax)3[3/Fant 2000/p482/col1/¶3]
‡Step 1 only.
1. Shiffman S, Ferguson SG. The effect of a nicotine patch on cigarette craving over the course of the day: results from two randomized clinical trials. Curr Med Res Opin. 2008;24(10):2795-2804. 2. DeVeaugh-Geiss AM, Chen LH, Kotler ML, Ramsay LR, Durcan MJ. Pharmacokinetic comparison of two nicotine transdermal systems, a 21-mg/24-hour patch and a 25-mg/16-hour patch: a randomized, open-label, single-dose, two-way crossover study in adult smokers. Clin Ther. 2010;32(6):1140-1148. 3. Fant RV, Henningfield JE, Shiffman S, Strahs KR, Reitberg DP. A pharmacokinetic crossover study to compare the absorption characteristics of three transdermal nicotine patches. Pharmacol Biochem Behav.
2000;67(3):479-482.Gore AV, Chien YW. The nicotine transdermal system. Clin Dermatol. 1998;16(5):599-615.